Recently, we were charged with providing a learning opportunity for high school students participating in the Upward Bound Regional Math and Science Program, a program designed to stimulate interest in mathematics and science for students from disadvantaged environments. Our challenge was to introduce students to the joys, excitement, and mystery of physiology and to stimulate their interest for future study. To this end, we developed a laboratory experience that examined basic physiological concepts in an animal model. This opportunity introduced students to how their bodies work and the importance of the use of animals in research. The students left the experience confident, motivated, and excited about learning.