Beta-endorphin response to endurance exercise: relationship to exercise dependence. 1993

E F Pierce, and N W Eastman, and H L Tripathi, and K G Olson, and W L Dewey
Department of Health and Sport Science, University of Richmond, Virginia 23173.

Considerable research has shown significant increases in beta-endorphin levels after aerobic activity. These increases and their accompanying euphoric effect have been suggested as a possible psychophysiological mechanism underlying the exercise-dependence syndrome. The relationship between plasma beta-endorphin levels and a tendency towards exercise dependence, however, has not been established. To examine this relationship, 8 women trained in aerobic dance completed an exercise-dependence assessment prior to participation in a 45-min. session of continuous aerobic dance. Plasma beta-endorphin concentration was measured both prior to and following the aerobics routine. A Student t test for paired observations indicated that mean plasma beta-endorphin levels (+/- SE) were significantly higher after the aerobics routine (11.96 +/- 1.3 pg beta-EP.ml-1) than preexercise levels (8.62 +/- 1.4). However, beta-endorphin difference values (% change) were not significantly correlated with scores on the exercise-dependence survey. Those data suggest that scores on exercise dependence are not related to changes in plasma beta-endorphin levels after aerobic exercise.

UI MeSH Term Description Entries
D010807 Physical Endurance The time span between the beginning of physical activity by an individual and the termination because of exhaustion. Endurance, Physical,Physical Stamina,Stamina, Physical
D010809 Physical Fitness The ability to carry out daily tasks and perform physical activities in a highly functional state, often as a result of physical conditioning. Fitness, Physical
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001615 beta-Endorphin A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPTORS and is an analgesic. Its first four amino acids at the N-terminal are identical to the tetrapeptide sequence of METHIONINE ENKEPHALIN and LEUCINE ENKEPHALIN. Endorphin, beta,beta-Endorphin (1-31),beta Endorphin
D015444 Exercise Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure. Aerobic Exercise,Exercise, Aerobic,Exercise, Isometric,Exercise, Physical,Isometric Exercise,Physical Activity,Acute Exercise,Exercise Training,Activities, Physical,Activity, Physical,Acute Exercises,Aerobic Exercises,Exercise Trainings,Exercise, Acute,Exercises,Exercises, Acute,Exercises, Aerobic,Exercises, Isometric,Exercises, Physical,Isometric Exercises,Physical Activities,Physical Exercise,Physical Exercises,Training, Exercise,Trainings, Exercise
D016739 Behavior, Addictive The observable, measurable, and often pathological activity of an organism that portrays its inability to overcome a habit resulting in an insatiable craving for a substance or for performing certain acts. The addictive behavior includes the emotional and physical overdependence on the object of habit in increasing amount or frequency. Addictive Behavior,Addictive Behaviors,Behaviors, Addictive

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