Biomaterial Database

[Effect of hemodialysis on left ventricular function in patients with chronic renal failure assessment with radionuclide ventriculography]. 1993

J Starzyk, and W Grzeszczak, and D Kowalski, and B Kaczmarska

Oddziału Nefrologii, Slaskiej Akademii Medycznej, Zabrzu.

To examine the effects of haemodialysis (HD) on left ventricular (LV) function, gated radionuclide ventriculography was conducted before and after HD in 16 patients with chronic renal failure (CRF) and in 12 healthy persons. The LV sectorial function was assessed by subdividing the LV region of interest into 6 sectors. Global ejection fraction (EF) was unchanged by dialysis (61.4 +/- 8.3% before vs. 63.5 +/- 10.4% after) (mean +/- S.D.). EF of sectors 4 and 5 was improved significantly (69.3 +/- 10.7% and 85.6 +/- 17.1% before vs. 81.7 +/- 18.4% and 97.4 +/- 22.0% after) (p < 0.05 and p < 0.05). The peak ejection rate (PER) was increased following HD (3.07 +/- 1.03 EDc/s before vs. 3.88 +/- 0.88 EDc/s after) (p < 0.02). The time to end systole (TES) corrected for R-R interval was unchanged by HD (46.3 +/- 6.3 before vs. 43.8 +/- 5.3 after). The peak filling rate (PFR) was unchanged by HD (3.41 +/- 0.77 EDc/s before vs. 3.05 +/- 0.45 EDc/s after). The time to peak filling rate (TPFR) corrected for R-R interval was increased (21.8 +/- 5.3 before vs 25.9 +/- 5.0 after) (p < 0.02). This study indicates that HD produces beneficial effects on LV systolic function in CRF patients and does not improve LV filling in early diastole.

UI	MeSH Term	Description	Entries
D007676	Kidney Failure, Chronic	The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.	ESRD,End-Stage Renal Disease,Renal Disease, End-Stage,Renal Failure, Chronic,Renal Failure, End-Stage,Chronic Kidney Failure,End-Stage Kidney Disease,Chronic Renal Failure,Disease, End-Stage Kidney,Disease, End-Stage Renal,End Stage Kidney Disease,End Stage Renal Disease,End-Stage Renal Failure,Kidney Disease, End-Stage,Renal Disease, End Stage,Renal Failure, End Stage
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D005260	Female		Females
D006435	Renal Dialysis	Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.	Dialysis, Extracorporeal,Dialysis, Renal,Extracorporeal Dialysis,Hemodialysis,Dialyses, Extracorporeal,Dialyses, Renal,Extracorporeal Dialyses,Hemodialyses,Renal Dialyses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D015635	Radionuclide Ventriculography	Imaging of a ventricle of the heart after the injection of a radioactive contrast medium. The technique is less invasive than cardiac catheterization and is used to assess ventricular function.	Ventriculography, Radionuclide
D016277	Ventricular Function, Left	The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.	Left Ventricular Function,Function, Left Ventricular,Functions, Left Ventricular,Left Ventricular Functions,Ventricular Functions, Left