BIOMAT Database Logo BIOMAT Database Logo

"Clubbing" -- a side-effect of long-term phenothiazines treatment. 1976

U Halbreich, and M Assael

A schizophrenic-paranoid patient was on a continuous maintenance treatment of phenothiazines for 5 years. 8 weeks after switching over to fluphenazine enanthlate injections intramuscularly, "clubbed fingers" occurred. The results of thorough examinations were within normal limits, so the phenothiazine treatment was presumed to be the cause of clubbing. It is suggested than anoxia of the distal tissue gives rise to clubbing due to arterial hypotension, slowing down of the blood and viscosity of the blood.

UI MeSH Term Description Entries
D008134 Long-Term Care Care over an extended period, usually for a chronic condition or disability, requiring periodic, intermittent, or continuous care. Care, Long-Term,Long Term Care
D008297 Male Males
D012039 Regional Blood Flow The flow of BLOOD through or around an organ or region of the body. Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D005385 Fingers Four or five slender jointed digits in humans and primates, attached to each HAND. Finger
D005476 Fluphenazine A phenothiazine used in the treatment of PSYCHOSES. Its properties and uses are generally similar to those of CHLORPROMAZINE. Flufenazin,Fluphenazine Hydrochloride,Lyogen,Prolixin,Hydrochloride, Fluphenazine
D006227 Hand Deformities, Acquired Deformities of the hand, or a part of the hand, acquired after birth as the result of injury or disease. Acquired Hand Deformities,Acquired Hand Deformity,Deformities, Acquired Hand,Deformity, Acquired Hand,Hand Deformity, Acquired
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012563 Schizophrenia, Paranoid A chronic form of schizophrenia characterized primarily by the presence of persecutory or grandiose delusions, often associated with hallucination. Delusional Disorder,Paranoid Schizophrenia,Delusional Disorders,Disorder, Delusional,Disorders, Delusional,Paranoid Schizophrenias,Schizophrenias, Paranoid
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

U Halbreich, and M Assael
A Side Effect of Phenothiazines.
November 1964, Canadian Medical Association journal,
U Halbreich, and M Assael
SIDE EFFECT OF PHENOTHIAZINES.
January 1965, Canadian Medical Association journal,
U Halbreich, and M Assael
Side effects of parenteral long-acting phenothiazines.
January 1972, British medical journal,
U Halbreich, and M Assael
The on-off effect - a side-effect of long-term levodopa treatment.
August 1978, Nursing mirror,
U Halbreich, and M Assael
An unusual side-effect of long-term methysergide treatment.
April 1995, Australian and New Zealand journal of medicine,
U Halbreich, and M Assael
Is Fatigue a Long-term Side Effect of Breast Cancer Treatment?
May 1999, Cancer control : journal of the Moffitt Cancer Center,
U Halbreich, and M Assael
Stuttering: an unusual side effect of phenothiazines.
March 1981, The American journal of psychiatry,
U Halbreich, and M Assael
[Tardive dystonia: a rare side effect after long-term neuroleptic treatment].
November 1982, Der Nervenarzt,
U Halbreich, and M Assael
[Long-term treatment of mental disorders with high doses of phenothiazines].
October 1959, Nederlands tijdschrift voor geneeskunde,
U Halbreich, and M Assael
Clubbing and hip pain in a long-term smoker.
March 2003, JAAPA : official journal of the American Academy of Physician Assistants,
Copied contents to your clipboard!