Biomaterial Database

Comparison of the automated random access immunoassay analysers, ACS-180 (Ciba Corning) and AIA-1200 (Tosoh). 1993

G M Costongs, and P C Janson

Dept. Clinical Chemistry, Maaslandziekenhuis, Sittard, The Netherlands.

Two random access immunoassay analysers, the ACS-180 (Ciba Corning) and the AIA-1200 (Tosoh Corp.) were compared with respect to performance and user-friendliness. Precision studies revealed an almost equal intra-assay variation coefficient, but day-to-day reproducibility was better on the AIA-1200. Recovery of dilution series of tumour markers was too high with the ACS-180. Both systems were free from carry-over effects, on account of the extra wash step in the ACS-180 (for thyrotropin, carcinoembryonic antigen and human chorionic gonadotropin) and the separate pipetting tip in the AIA-1200. Reagent stability is better in the AIA-1200 than in the ACS-180. The AIA-1200 is more user-friendly and produces a higher throughput than the ACS-180 in daily routine operation (92 results/hour vs. 78 results/hour).

UI	MeSH Term	Description	Entries
D007118	Immunoassay	A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.	Immunochromatographic Assay,Assay, Immunochromatographic,Assays, Immunochromatographic,Immunoassays,Immunochromatographic Assays
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D001774	Blood Chemical Analysis	An examination of chemicals in the blood.	Analysis, Blood Chemical,Chemical Analysis, Blood,Analyses, Blood Chemical,Blood Chemical Analyses,Chemical Analyses, Blood
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D012680	Sensitivity and Specificity	Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	Specificity,Sensitivity,Specificity and Sensitivity