The authors built an automatic CT-driven device by which 3D models of biologic structures can be obtained. Original bidimensional densitometric data are recorded on tape and transferred to a mechanical computer-driven arm capable of cutting polystyrene slices reproducing the original biologic structures by means of an original software. The aim of our research was to assess the feasibility of such a device from a practical point of view and to analyze and solve related problems, in order to use the experience thus gained to develop more complex systems. We deliberately set up a device both technologically advanced and simple to be used even by non-specifically trained operators. The system capabilities open new perspectives in many application fields, such as surgery (stereotactic procedures, the making of personalized prostheses, plastic surgery, procedures planning and simulation), treatment (stereotactic radiotherapy), diagnostics (stereotactic biopsy) and educational use.