-transparent.png){kind=logo}
Rats were trained to discriminate between an intracerebroventricular injection of 1.15 nmol of Neuropeptide Y (NPY) and a sham injection. Rats rapidly learned to press the appropriate lever during training. NPY's discriminative stimulus effects were compared to those of saline, and 1.15-3.45 nmol [Leu31,Pro34]NPY, a Y1 receptor agonist and NPY 20-36, Y2 receptor agonist. [Leu31,Pro34]NPY resulted in NPY-appropriate responding, whereas saline and NPY 20-36 did not. [Leu31,Pro34]NPY also increased food intake, but NPY 20-36 did not. This suggests that NPY's discriminative stimulus and orexigenic effects involve the Y1, but not the Y2, receptor.
Related Publications
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
January 1992,
Neuroscience letters,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
January 1990,
Proceedings of the National Academy of Sciences of the United States of America,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
August 1994,
Regulatory peptides,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
July 1993,
The Journal of pharmacology and experimental therapeutics,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
August 1998,
Neuroscience letters,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
December 2017,
Neuropeptides,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
February 1998,
Pharmacology, biochemistry, and behavior,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
November 1994,
Neuropeptides,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
March 1997,
Brain research,
D C Jewett, and
J Cleary, and
D W Schaal, and
T Thompson, and
A S Levine
January 1995,
Journal of receptor and signal transduction research,
