Biomaterial Database

[Transtympanic electrocochleography in Menière's disease]. 1993

C S Chen, and Y C Wong

Department of Otolaryngology, Veterans General Hospital-Taipei, Taiwan, R.O.C.

In order to examine the usefulness of the electrocochleography (ECoG) in the diagnosis of Menière's disease and establish the diagnostic criteria in Chinese, transtympanic ECoG was performed on 18 normal ears, 22 Menière's ears and 14 ears with cochlear type sensorineural hearing loss other than Menière's disease. Although the Menière's ears had larger mean summating potential (SP) than the normal ears, the difference between both groups was not statistically significant. The mean amplitude and latency of the action potential (AP) in Menière's ears decreased and elongated significantly, but neither was sensitive enough in diagnosing Menière's disease. The SP/AP amplitude ratio not only made significant difference among 3 groups, but also had good diagnostic sensitivity (59.1%) and specificity (92%) in diagnosing Menière's disease while using the 95% upper confidence limit of the normative data (i.e., 34%). The SP/AP amplitude ratio of Menière's ears tended to increase while the mean hearing level of 4-8 KHz deteriorated. Also, abnormal enlargement of the SP/AP amplitude ratio in Menière's disease tended to be the result of decreased AP amplitude.

UI	MeSH Term	Description	Entries
D008575	Meniere Disease	A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.	Meniere's Disease,Meniere's Syndrome,Vertigo, Aural,Auditory Vertigo,Aural Vertigo,Ménière Disease,Ménière's Disease,Ménière's Vertigo,Otogenic Vertigo,Auditory Vertigos,Disease, Meniere,Disease, Meniere's,Disease, Ménière,Disease, Ménière's,Diseases, Ménière,Diseases, Ménière's,Meniere Syndrome,Menieres Disease,Menieres Syndrome,Ménière Diseases,Ménière Vertigo,Ménière's Diseases,Ménière's Vertigos,Ménières Disease,Ménières Vertigo,Otogenic Vertigos,Syndrome, Meniere's,Vertigo, Auditory,Vertigo, Ménière's,Vertigo, Otogenic,Vertigos, Auditory,Vertigos, Ménière's,Vertigos, Otogenic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000200	Action Potentials	Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.	Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential
D001300	Audiometry, Evoked Response	A form of electrophysiologic audiometry in which an analog computer is included in the circuit to average out ongoing or spontaneous brain wave activity. A characteristic pattern of response to a sound stimulus may then become evident. Evoked response audiometry is known also as electric response audiometry.	Audiometry, Electroencephalic Response,Electrocochleography,Evoked Response Audiometry,Audiometries, Electroencephalic Response,Audiometries, Evoked Response,Electrocochleographies,Electroencephalic Response Audiometries,Electroencephalic Response Audiometry,Evoked Response Audiometries,Response Audiometries, Electroencephalic,Response Audiometries, Evoked,Response Audiometry, Electroencephalic,Response Audiometry, Evoked