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Platelets from 103 patients with chronic coronary heart disease were studied electron microscopically, cytochemically, fluorescence microscopically and with radionuclides. The platelets showed polymorphism indicated by diverse sizes, various content of alpha-granules in platelets, emergence of degenerative hyperosmiophilic forms. Shorter life cycle of the platelets was observed in line with a compensatory increase in the number of their immature forms. Abundance of reversibly and irreversibly activated and degranulated cells impaired platelet aggregation. These changes entailed rearrangement of platelet glycocalyx. The findings evidence noticeable structural shifts in platelets which diminish their resistance to factors stimulating atherogenesis and underlying aggravations of coronary heart disease.
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
January 1984,
Biulleten' eksperimental'noi biologii i meditsiny,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
October 1970,
Kardiologiia,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
January 1985,
Vutreshni bolesti,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
January 1987,
Klinicheskaia meditsina,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
August 1981,
Kardiologiia,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
January 1988,
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
April 1987,
Vrachebnoe delo,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
September 1989,
Kardiologiia,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
January 1982,
Vrachebnoe delo,
A S Gavrish, and
O V Sergienko, and
T I Ivashchenko, and
E N Poradun
February 1989,
Kardiologiia,
