-transparent.png){kind=logo}
To evaluate the acute effect of human erythropoietin (r-HuEPO) on basal and stimulated prolactin (PRL) secretion, 18 normal subjects (12 females, 6 males) were studied. The PRL response to thyrotropin-releasing hormone (TRH; 200 micrograms intravenously, n = 7), metoclopramide (MCP, 20 mg intravenously, n = 5) and fenfluramine (FF, 60 mg os, n = 6) was tested in presence of saline or r-HuEPO (30 U/kg intravenously). The drug neither modified basal PRL levels nor affected the normal PRL release to TRH, MCP and FF. Our results indicate that, in normal subjects, the acute administration of therapeutic doses of r-HuEPO does not interfere with PRL secretion both after a direct pituitary stimulus and after stimuli involving dopaminergic and serotoninergic pathways.
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
December 1976,
Bollettino della Societa italiana di biologia sperimentale,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
January 1985,
Clinical neuropharmacology,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
March 1977,
Hiroshima journal of medical sciences,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
February 1974,
Nihon Naibunpi Gakkai zasshi,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
February 1978,
Bollettino della Societa italiana di biologia sperimentale,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
February 1977,
Life sciences,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
January 1980,
Medicina clinica,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
December 1978,
Bollettino della Societa italiana di biologia sperimentale,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
June 1982,
The Journal of clinical endocrinology and metabolism,
G P Bernini, and
F Mariotti, and
G Brogi, and
F Cerri, and
M Santoni, and
F Ciardella, and
F Franchi
January 1981,
Hormone research,
