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Serial studies of adaptation to aortic regurgitation (AR) were undertaken to determine whether sonomicrometry and echocardiography could be combined to measure changes in left ventricular (LV) cavitary volume (Vlv) and wall mass using the geometric formula [Vlv = K pi b2 alpha--wall volume], where K is a constant depending on the geometric model and a and be are epicardial major- and minor-axis diameters, respectively. Postmortem studies were performed in six normal dogs and in nine with AR; ultrasonic ventricular dimensions were measured as Vlv was varied with an intracavitary balloon. Three models were tested: 1) ellipsoid (model I; K = 1/6), 2) cylinder-ellipsoid (model II; K = 5/24), and 3) cylinder (model III; K = 1/4). The slope of the relationship between calculated Vlv and balloon volume varied between models (I, 0.71 +/- 0.11; II, 0.89 +/- 0.14; III, 1.07 +/- 0.17), and empiric determination of K to produce a slope of 1.0 resulted in a value of 0.26 +/- 0.04, not significantly different from the cylindrical model. Serial measurements of LV dimensions in 10 chronically instrumented conscious dogs revealed no significant change in end-diastolic or end-ejection LV shape after up to 16 wk of AR. Sonomicrometry and echocardiography can be integrated using a cylindrical geometric model to accurately estimate changes in end-diastolic or end-ejection Vlv during chronic volume overload.
J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
September 1991,
Circulation,
J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
February 1989,
Transplantation proceedings,
J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
April 1996,
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J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
February 1985,
Japanese circulation journal,
J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
January 1965,
Actualites cardiologiques et angeiologiques internationales,
J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
August 1987,
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J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
September 1991,
Cardiovascular research,
J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
December 1987,
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J W Gaynor, and
M P Feneley, and
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G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
June 2003,
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
J W Gaynor, and
M P Feneley, and
S A Gall, and
G W Maier, and
J A Kisslo, and
J W Davis, and
J S Rankin, and
D D Glower
November 1970,
American journal of veterinary research,
