Biomaterial Database

Epidermotropic neutrophilic granulocytes express MAC-1 (CD11b/CD18) rather than LFA-1 (CD11a/CD18). 1993

P von den Driesch

Hautklinik der Universität Erlangen-Nürnberg, Germany.

UI	MeSH Term	Description	Entries
D009504	Neutrophils	Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.	LE Cells,Leukocytes, Polymorphonuclear,Polymorphonuclear Leukocytes,Polymorphonuclear Neutrophils,Neutrophil Band Cells,Band Cell, Neutrophil,Cell, LE,LE Cell,Leukocyte, Polymorphonuclear,Neutrophil,Neutrophil Band Cell,Neutrophil, Polymorphonuclear,Polymorphonuclear Leukocyte,Polymorphonuclear Neutrophil
D004817	Epidermis	The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012871	Skin Diseases	Diseases involving the DERMIS or EPIDERMIS.	Dermatoses,Skin and Subcutaneous Tissue Disorders,Dermatosis,Skin Disease
D013492	Suppuration	A pathologic process consisting in the formation of pus.	Pus
D016169	Lymphocyte Function-Associated Antigen-1	An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (CD18 ANTIGENS) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.	LFA-1,Leukocyte Function Associated Antigen-1,Integrin alphaLbeta2,Antigen-1, Lymphocyte Function-Associated,Lymphocyte Function Associated Antigen 1,alphaLbeta2, Integrin
D016177	Macrophage-1 Antigen	An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.	CR3 Receptor,Complement 3 Receptor,Integrin alphaMbeta2,Mac-1 Antigen,Receptor, Complement 3,Adhesive Receptor Mac-1,Integrin alpha(M)beta(2),Integrin alpha-M beta-2,Mac-1 Adhesive Receptor,Mac-1 Receptor,Mo1 Antigen Receptor,Mo1 Glycoprotein Receptor,Receptor, CR3,Receptor, Mo1 Antigen,Receptor, Mo1 Glycoprotein,Adhesive Receptor, Mac-1,Antigen Receptor, Mo1,Antigen, Macrophage-1,Glycoprotein Receptor, Mo1,Integrin alpha M beta 2,Mac 1 Adhesive Receptor,Mac 1 Antigen,Mac 1 Receptor,Macrophage 1 Antigen,Receptor, Mac-1 Adhesive,alpha-M beta-2, Integrin,alphaMbeta2, Integrin