-transparent.png){kind=logo}
Five metabolites were detected in the plasma and urine of a patient following ingestion of the organophosphate insecticide, phenthoate. Intact phenthoate was detected only in gastric lavage fluid. After methylation of acidic extracts of plasma and urine, phenthoate acid, demethyl phenthoate, demethyl phenthoate oxon acid, demethyl phenthoate S-isomer, and demethyl phenthoate acid S-isomer were identified with synthesized phenthoate analogues by gas chromatography and gas chromatograph-mass spectrometry. The main metabolites were phenthoate acid and demethyl phenthoate oxon acid. Although demethyl phenthoate oxon acid was a significant metabolite, no phenthoate oxon, phenthoate oxon acid or demethyl phenthoate oxon were detected. If the oxon was formed in the patient, it may have been rapidly degraded by carboxylesterase or glutathione transferase to demethyl phenthoate oxon acid.
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
November 2018,
Journal of forensic sciences,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
February 2022,
Clinical toxicology (Philadelphia, Pa.),
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
February 2001,
Forensic science international,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
February 1997,
Annals of internal medicine,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
January 1999,
Journal of toxicology. Clinical toxicology,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
July 1984,
Toxicology letters,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
July 1981,
Archives of environmental contamination and toxicology,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
August 2007,
Bulletin of environmental contamination and toxicology,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
November 2004,
Bulletin of environmental contamination and toxicology,
S Kawabata, and
M Hayasaka, and
H Hayashi, and
M Sakata, and
Y Hatakeyama, and
N Ogura
May 1984,
Bulletin of environmental contamination and toxicology,
