Biomaterial Database

[Perioperative antibiotic prophylaxis in maxillofacial surgery]. 1993

H A Merten, and F Halling

Abt. Kieferchirurgie, Zentrum Zahn-Mund- und Kieferheilkunde, Universitätsklinik, Göttingen.

In surgical interventions in the maxillofacial area the intraoral approach often is chosen for technical and esthetic reasons. Because of the inevitable contamination of the surgical wounds with the facultative pathogenic mixed flora of the oral cavity, these operations are exposed to an increased risk of postoperative wound infections. Therefore, a perioperative antibiotic prophylaxis is justified. In a prospective, controlled open study in 112 patients the effect of a preoperative one-shot prophylaxis with cefuroxime was compared with that of a short-term prophylaxis for 48 hours. The low rates of postoperative infectious complications in both groups (3.5 resp. 4.5%) verify the efficacy of the perioperative antibiotic prophylaxis in head and neck surgery. For microbiological, practical and economic aspects however, the one-shot-prophylaxis should be preferred.

UI	MeSH Term	Description	Entries
D007262	Infusions, Intravenous	The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.	Drip Infusions,Intravenous Drip,Intravenous Infusions,Drip Infusion,Drip, Intravenous,Infusion, Drip,Infusion, Intravenous,Infusions, Drip,Intravenous Infusion
D008297	Male		Males
D008437	Maxilla	One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.	Maxillae,Maxillary Bone,Bone, Maxillary,Bones, Maxillary,Maxillary Bones,Maxillas
D011292	Premedication	Preliminary administration of a drug preceding a diagnostic, therapeutic, or surgical procedure. The commonest types of premedication are antibiotics (ANTIBIOTIC PROPHYLAXIS) and anti-anxiety agents. It does not include PREANESTHETIC MEDICATION.	Premedications
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D002444	Cefuroxime	Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.	Cephuroxime,Ketocef,Zinacef
D004334	Drug Administration Schedule	Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.	Administration Schedule, Drug,Administration Schedules, Drug,Drug Administration Schedules,Schedule, Drug Administration,Schedules, Drug Administration
D005145	Face	The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.	Faces
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man