Biomaterial Database

[Changes in epidural pressure during epidural injection]. 1993

T Fukushige, and T Yoneda, and T Muteki

Department of Anesthesiology, Kurume University School of Medicine.

To evaluate the change of epidural pressure when local anesthetic was injected into epidural space, we inserted three epidural catheters in 13 patients. Epidural catheters were inserted at Th8/9, Th10/11 and L3/4 intervertebral spaces, and 2% mepivacaine 10 ml was injected through Th10/11 or L3/4 catheter. The change of epidural pressure was recorded from three catheters. The elevation of pressure was largest in the injected catheter, but the pattern of elevation was similar in all three catheters. The results suggest that the elevation of epidural pressure occurs at the same time all over the epidural space when local anesthetic is injected.

UI	MeSH Term	Description	Entries
D007268	Injections, Epidural	The injection of drugs, most often analgesics, into the spinal canal without puncturing the dura mater.	Epidural Injections,Extradural Injections,Peridural Injections,Injections, Extradural,Injections, Peridural,Epidural Injection,Extradural Injection,Injection, Epidural,Injection, Extradural,Injection, Peridural,Peridural Injection
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011312	Pressure	A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Pressures
D002404	Catheterization	Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.	Cannulation,Cannulations,Catheterizations
D004824	Epidural Space	Space between the dura mater and the walls of the vertebral canal.	Epidural Spaces,Space, Epidural,Spaces, Epidural
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D000779	Anesthetics, Local	Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.	Anesthetics, Conduction-Blocking,Conduction-Blocking Anesthetics,Local Anesthetic,Anesthetics, Topical,Anesthetic, Local,Anesthetics, Conduction Blocking,Conduction Blocking Anesthetics,Local Anesthetics,Topical Anesthetics