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We have established IgG rheumatoid factor (RF)-secreting hybridoma cell lines from the synovial tissues of two patients (TS and SJ) with rheumatoid arthritis (RA) and one (KL) with the polyarticular form of juvenile rheumatoid arthritis (JRA). The IgG RF bind human and rabbit IgG and all except one form intracellular complement-fixing complexes indicative of a self-association process. The possibility of IgG RF for self association and immune complex formation is a feature thought to be important for the inflammatory processes in RA. Of the IgG RF-secreting cell lines established, three clones from patient SJ and one from patient KL are of the IgG1 kappa isotype while five clones from patient TS are of the IgG2 lambda isotype.
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
August 1972,
Clinica chimica acta; international journal of clinical chemistry,
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
April 1993,
The Journal of rheumatology,
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
January 1993,
Clinical immunology and immunopathology,
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
June 1989,
British journal of rheumatology,
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
January 2018,
Methods in molecular biology (Clifton, N.J.),
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
June 2001,
Clinical science (London, England : 1979),
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
April 2007,
Inflammation research : official journal of the European Histamine Research Society ... [et al.],
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
January 1993,
Autoimmunity,
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
April 1977,
Arthritis and rheumatism,
I Randen, and
K M Thompson, and
S J Thorpe, and
O Førre, and
J B Natvig
July 1999,
The Journal of rheumatology,
