Biomaterial Database

State of spermatogenesis in rats flown aboard the biosatellite Cosmos-690. 1977

G I Plakhuta-Plakutina

Testes of 30 rats flown aboard the biosatellite Cosmos-690 for 20.5 d and 30 rats kept in a ground-based experiment, which simulated all flight except weightlessness and accleration, were examined morphologically. On the 10th experimental day the rats were exposed for 24 h to gamma irradiation from a Cs137 source at doses of 220, 800, and 955 rad. Tests from 60 nonirradiated rats that remained in the vivarium were used as controls. On the 1st-2nd and 26-27th post-experimental days the animals showed a significant decrease in the weight of testes, post-radiation death of spermatogonia, and important structural changes in the spermatogenic epithelium, whose level depended on the dose of irradiation and the time elapsed after the exposure. No significant differences in the weight of testes, frequency of occurrence of individual components of the spermatogenic epithelium, and time of emergence of reparative processes were noted. No modifying effect of space flight factors on the development of radiation-induced changes in the spermatogenic epithelium of rats was found.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D011839	Radiation, Ionizing	ELECTROMAGNETIC RADIATION or particle radiation (high energy ELEMENTARY PARTICLES) capable of directly or indirectly producing IONS in its passage through matter. The wavelengths of ionizing electromagnetic radiation are equal to or smaller than those of short (far) ultraviolet radiation and include gamma and X-rays.	Ionizing Radiation,Ionizing Radiations,Radiations, Ionizing
D005720	Gamma Rays	Penetrating, high-energy electromagnetic radiation emitted from atomic nuclei during NUCLEAR DECAY. The range of wavelengths of emitted radiation is between 0.1 - 100 pm which overlaps the shorter, more energetic hard X-RAYS wavelengths. The distinction between gamma rays and X-rays is based on their radiation source.	Gamma Wave,Gamma Radiation,Nuclear X-Rays,Radiation, Gamma,X-Rays, Nuclear,Gamma Radiations,Gamma Ray,Gamma Waves,Nuclear X Rays,Nuclear X-Ray,Ray, Gamma,Wave, Gamma,Waves, Gamma,X Rays, Nuclear,X-Ray, Nuclear
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013026	Space Flight	Travel beyond the earth's atmosphere.	Space Exploration,Space Travel,Spaceflight,Exploration, Space,Explorations, Space,Flight, Space,Flights, Space,Space Explorations,Space Flights,Space Travels,Spaceflights,Travel, Space,Travels, Space
D013091	Spermatogenesis	The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.	Spermatocytogenesis,Spermiogenesis
D013737	Testis	The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.	Testicles,Testes,Testicle
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus