-transparent.png){kind=logo}
To examine the effect of prefeeding the aldose reductase inhibitor (ARI) on the cataract induced by the subsequent feeding of galactose diet, rats were first fed rat chow with or without ARI for 2 weeks. The animals were then transferred to a 25% galactose diet for different periods of time. Lenses were enucleated and examined by light microscopy. The amount of galactitol in the lenses was examined biochemically. The cataract was less severe and there was less galactitol in the lenses in the rats first fed with ARI than in those without ARI. These results indicate that the feeding the ARI prior to galactose feeding partly inhibits galactose cataract.
Related Publications
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
October 1989,
Current eye research,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
February 1987,
Nippon Ganka Gakkai zasshi,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
February 1990,
Nippon Ganka Gakkai zasshi,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
February 1982,
Investigative ophthalmology & visual science,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
November 1989,
Nippon Ganka Gakkai zasshi,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
January 1993,
Japanese journal of ophthalmology,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
January 1985,
Diabetes,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
November 2010,
Nihon rinsho. Japanese journal of clinical medicine,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
January 1991,
Developments in ophthalmology,
T Tsuji, and
S Okamoto, and
H Ikebe, and
H Terubayashi, and
Y Akagi, and
T Tanimoto
November 1991,
Investigative ophthalmology & visual science,
