Biomaterial Database

[Molecular biology of apolipoproteins in genesis of hyperlipidemias and atherosclerosis]. 1993

Y Hata

Department of Medicine and Gerontology, Kyorin University School of Medicine.

The application of cell and molecular biology techniques has provided new information on the structure and function of the apolipoproteins, enzymes and receptors that mediate lipoprotein transport. The identification of human mutations at the gene level has established the molecular basis for several clinically important dialipoproteinemias and atherosclerosis.

UI	MeSH Term	Description	Entries
D006949	Hyperlipidemias	Conditions with excess LIPIDS in the blood.	Hyperlipemia,Hyperlipidemia,Lipemia,Lipidemia,Hyperlipemias,Lipemias,Lipidemias
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001053	Apolipoproteins	Protein components on the surface of LIPOPROTEINS. They form a layer surrounding the hydrophobic lipid core. There are several classes of apolipoproteins with each playing a different role in lipid transport and LIPID METABOLISM. These proteins are synthesized mainly in the LIVER and the INTESTINES.	Apolipoprotein
D001161	Arteriosclerosis	Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.	Arterioscleroses

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