Biomaterial Database

Olfactory neuroblastoma: an ultrastructural study. 1977

J B Taxy, and D F Hidvegi

The ultrastructural features of two olfactory neuroblastomas are reported. By means of light microscopy, one was well differentiated while the other was a poorly differentiated, small cell neoplasm. The latter case required ultrastructural examination to establish the diagnosis. Electron microscopy of human tumors for diagnostic purposes may be particularly helpful in deciphering small, round cell tumors. Catecholamines were not biochemically detected in a portion of recurrent tumor from Case 2. The significance of this is equivocal in view of the limited previous biochemical studies of this neoplasm. However, by both light and electron microscopy, the morphology of olfactory and sympathetic neuroblastomas are strikingly similar.

UI	MeSH Term	Description	Entries
D009669	Nose Neoplasms	Tumors or cancer of the NOSE.	Cancer of Nose,Nasal Neoplasms,Nose Cancer,Cancer of the Nose,Nasal Cancer,Neoplasms, Nose,Cancer, Nasal,Cancer, Nose,Cancers, Nasal,Cancers, Nose,Nasal Cancers,Nasal Neoplasm,Neoplasm, Nasal,Neoplasm, Nose,Neoplasms, Nasal,Nose Cancers,Nose Neoplasm
D002395	Catecholamines	A general class of ortho-dihydroxyphenylalkylamines derived from TYROSINE.	Catecholamine,Sympathin,Sympathins
D002454	Cell Differentiation	Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.	Differentiation, Cell,Cell Differentiations,Differentiations, Cell
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D012583	Schwann Cells	Neuroglial cells of the peripheral nervous system which form the insulating myelin sheaths of peripheral axons.	Schwann Cell,Cell, Schwann,Cells, Schwann
D018241	Neuroectodermal Tumors, Primitive, Peripheral	A group of highly cellular primitive round cell neoplasms which occur extracranially in soft tissue and bone and are derived from embryonal neural crest cells. These tumors occur primarily in children and adolescents and share a number of characteristics with EWING SARCOMA.	Neuroectodermal Tumor, Peripheral,Peripheral Primitive Neuroectodermal Tumor,Peripheral Primitive Neuroectodermal Tumors,(pPNET) Peripheral Primitive Neuroectodermal Tumors,Extracranial Primitive Neuroectodermal Tumor,Neuroectodermal Neoplasm, Peripheral Primitive,Neuroectodermal Tumor, Peripheral Primitive,Neuroepithelioma, Peripheral,Peripheral Primitive Neuroectodermal Neoplasm,Primitive Neuroectodermal Tumor, Extracranial,Neuroectodermal Tumors, Peripheral,Neuroepitheliomas, Peripheral,Peripheral Neuroectodermal Tumor,Peripheral Neuroectodermal Tumors,Peripheral Neuroepithelioma,Peripheral Neuroepitheliomas,Tumor, Peripheral Neuroectodermal,Tumors, Peripheral Neuroectodermal