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Detection and correction of patient motion in dynamic and static myocardial SPECT using a multi-detector camera. 1993

G Germano, and T Chua, and P B Kavanagh, and H Kiat, and D S Berman
Department of Medical Physics and Imaging, Cedars-Sinai Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.

We have developed a method for the detection and correction of translational patient motion in dynamic and static myocardial SPECT studies. The method uses a low activity 99mTc point source and is especially designed for multi-detector cameras. The source's centroid coordinates are measured or derived for all projection images in a temporal frame. The coordinate curves fitted to predicted distributions and the projection images shifted to realign measured to fitted values, with sub-pixel accuracy. In dynamic studies, the frame with the best fits serves as reference for all others. The accuracy of this method, measured with cardiac phantom experiments, was found to be +/- 0.37 mm and +/- 0.44 mm in the axial and transaxial dimension, respectively. By comparison, overall motion in 42 patients undergoing 99mTc-teboroxime dynamic cardiac SPECT studies was +/- 1.6 mm and +/- 1.2 mm, respectively (average on 39,272 projection views). Application of the method to phantom experiments, 99mTc-sestamibi and 99mTc-teboroxime human studies visually eliminated artifactual perfusion defects from simulated phantom motion and actual patient motion.

UI MeSH Term Description Entries
D008961 Models, Structural A representation, generally small in scale, to show the structure, construction, or appearance of something. (From Random House Unabridged Dictionary, 2d ed) Model, Structural,Structural Model,Structural Models
D009068 Movement The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior. Movements
D010091 Oximes Compounds that contain the radical R2C Aldoximes,Hydroxyimino Compounds,Ketoxime,Ketoximes,Oxime,Compounds, Hydroxyimino
D010361 Patients Individuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures. Clients,Client,Patient
D006321 Heart The hollow, muscular organ that maintains the circulation of the blood. Hearts
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015609 Organotechnetium Compounds Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents. Compounds, Organotechnetium
D015899 Tomography, Emission-Computed, Single-Photon A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image. CAT Scan, Single-Photon Emission,CT Scan, Single-Photon Emission,Radionuclide Tomography, Single-Photon Emission-Computed,SPECT,Single-Photon Emission-Computed Tomography,Tomography, Single-Photon, Emission-Computed,Single-Photon Emission CT Scan,Single-Photon Emission Computer-Assisted Tomography,Single-Photon Emission Computerized Tomography,CAT Scan, Single Photon Emission,CT Scan, Single Photon Emission,Emission-Computed Tomography, Single-Photon,Radionuclide Tomography, Single Photon Emission Computed,Single Photon Emission CT Scan,Single Photon Emission Computed Tomography,Single Photon Emission Computer Assisted Tomography,Single Photon Emission Computerized Tomography,Tomography, Single-Photon Emission-Computed
D015902 Gamma Cameras Electronic instruments that produce photographs or cathode-ray tube images of the gamma-ray emissions from organs containing radionuclide tracers. Scintillation Cameras,Nuclear Cameras,Scinti-Cameras,Camera, Gamma,Camera, Nuclear,Camera, Scintillation,Cameras, Gamma,Cameras, Nuclear,Cameras, Scintillation,Gamma Camera,Nuclear Camera,Scinti Cameras,Scinti-Camera,Scintillation Camera

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