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Purpurogallin, a flavinol obtainable from oak nutgalls, prevented lysis of human erythrocytes exposed to an azo-initiator of peroxyl radicals [2,2'-azo-bis (2-amidinopropane) dihydrochloride] at 37 degrees C. The percentage of this inhibition of erythrocyte lysis varied with the concentration of purpurogallin. In this system, the effect of purpurogallin surpassed those of lactosylphenyl-trolox, trolox and ascorbate, while mannitol, superoxide dismutase and/or catalase were without effect. While other concurrent mechanisms may be involved in purpurogallin action, it would appear that the amphipathic (both hydrophilic and lipophilic) nature of this flavinol and of trolox and lactosylphenyl-trolox, is an important factor. In fact, these three antioxidants, with purpurogallin as the best red cell protector here, excelled the protective effects of the other more hydrophilic antioxidants.
H Sugiyama, and
K P Fung, and
T W Wu
April 2000,
The Journal of pharmacy and pharmacology,
H Sugiyama, and
K P Fung, and
T W Wu
July 1994,
Biochemistry and molecular biology international,
H Sugiyama, and
K P Fung, and
T W Wu
January 1998,
Biochemistry and cell biology = Biochimie et biologie cellulaire,
H Sugiyama, and
K P Fung, and
T W Wu
May 1996,
Mechanisms of ageing and development,
H Sugiyama, and
K P Fung, and
T W Wu
November 2001,
Biochimica et biophysica acta,
H Sugiyama, and
K P Fung, and
T W Wu
November 2013,
Food chemistry,
H Sugiyama, and
K P Fung, and
T W Wu
September 2021,
Polymers,
H Sugiyama, and
K P Fung, and
T W Wu
January 2003,
Zeitschrift fur Naturforschung. C, Journal of biosciences,
H Sugiyama, and
K P Fung, and
T W Wu
May 2004,
Organic letters,
H Sugiyama, and
K P Fung, and
T W Wu
April 1997,
Antimicrobial agents and chemotherapy,
