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Intricate aspects of sarcoidosis course are studied. Examination included 75 Russian patients with sarcoidosis of the respiratory organs: 44 of them had newly diagnosed process and its spontaneous regression and in 31 the disease took a recurrent course. In all patients the HLA system of classes I and II were detected by means of a standard microlymphocytotoxic test; electrophoresis in polyacrylamide and starch gels was used to determine the genotypes of erythrocyte enzymes and/the groups of specific proteins. In sarcoidosis patients the rate of occurrence of antigens B7 and B8 was characteristically increased (22.7 and 27.3%) as compared to the group of healthy subjects (21.5 and 15.1%) and there was a rise of total homozygosity and heterozygosity reduction for the ESD, ACP, PGM-1 loci, which obviously may affect the disease course. Investigations are in progress.
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
January 1985,
Psychotherapie, Psychosomatik, medizinische Psychologie,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
July 2003,
JOP : Journal of the pancreas,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
January 2006,
TSitologiia i genetika,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
January 1977,
Terapevticheskii arkhiv,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
August 1968,
Nordisk medicin,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
May 1981,
The Proceedings of the Nutrition Society,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
November 2008,
Thrombosis and haemostasis,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
March 2021,
Terapevticheskii arkhiv,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
September 1966,
Vrachebnoe delo,
K A Dushimbekova, and
V V Romanov, and
L E Pospelov
March 1980,
Psychiatry research,
