[Revascularization measures after acute myocardial infarct]. 1993

R Erbel, and M Spiecker, and H J Rupprecht, and H Darius, and G Görge, and M Haude, and U Dietz, and J Meyer
Abteilung Kardiologie, Universität-Gesamthochschule Essen.

Thrombolytic therapy in acute myocardial infarction reduces mortality significantly. This acute effect seems to be counterbalanced by the increased mortality during follow-up whether or not the patient has been treated with thrombolytic therapy. Thrombolysis seems to be a first step in the treatment of acute myocardial infarction. Revascularization procedures are able to improve patient prognosis. Long-term follow-up demonstrated this fact whether or not PTCA was performed in the acute setting or on an elective basis. The 6-year survival was 80%. This survival rate was higher for patients who underwent PTCA than for those who were not undergoing PTCA and those who had no reperfusion of the coronary artery. The best prognosis was found for patients with coronary bypass surgery, indicating that revascularization should be the aim of treatment. The 6-year survival rate was found to be 92% and is thus in the range of patients with coronary artery disease. Acute infarct PTCA is limited to patients with cardiogenic shock and is particularly useful for patients with occlusion of the main stem of the left coronary artery. Acute infarct PTCA is also recommended in patients with contraindications for thrombolytic therapy, when interventions can be performed rapidly, when a large infarct size is present and infarct time is less than 4 hours. Whether or not RESCUE-PTCA should be recommended is under investigation. Patients with an open coronary artery have a better prognosis than patients with occluded coronary arteries, but during the acute stage, spontaneous recanalization is present in many patients. The RESCUE study will address this question. Elective PTCA is recommended as well as coronary bypass surgery, when successful reperfusion is achieved and one-or two-vessel disease is present or there is a two- or three-vessel disease or main stem involvement, respectively. In patients with coronary lesions less than 70% conservative treatment is useful. The guidelines of the American College of Cardiology and the American Heart Association are strongly recommended.

UI MeSH Term Description Entries
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D009204 Myocardial Revascularization The restoration of blood supply to the myocardium. (From Dorland, 28th ed) Internal Mammary Artery Implantation,Myocardial Revascularizations,Revascularization, Myocardial,Revascularizations, Myocardial
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D003131 Combined Modality Therapy The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used. Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001026 Coronary Artery Bypass Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion. Aortocoronary Bypass,Bypass, Coronary Artery,Bypass Surgery, Coronary Artery,Coronary Artery Bypass Grafting,Coronary Artery Bypass Surgery,Aortocoronary Bypasses,Artery Bypass, Coronary,Artery Bypasses, Coronary,Bypass, Aortocoronary,Bypasses, Aortocoronary,Bypasses, Coronary Artery,Coronary Artery Bypasses
D012770 Shock, Cardiogenic Shock resulting from diminution of cardiac output in heart disease. Cardiogenic Shock
D015906 Angioplasty, Balloon, Coronary Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply. Angioplasty, Coronary Balloon,Angioplasty, Transluminal, Percutaneous Coronary,Coronary Angioplasty, Transluminal Balloon,Percutaneous Transluminal Coronary Angioplasty,Balloon Dilation, Coronary Artery,Transluminal Coronary Balloon Dilation,Angioplasties, Coronary Balloon,Balloon Angioplasties, Coronary,Balloon Angioplasty, Coronary,Coronary Balloon Angioplasties,Coronary Balloon Angioplasty

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