Biomaterial Database

[Input pattern from the superior colliculus to vertical eye movement-motoneurons in the cat]. 1993

Y Sasaki

Department of Ophthalmology, Faculty of Medicine, Tottori University, Yonago, Japan.

The superior colliculus (SC) plays an important role in the transformation from visual and auditory signals to motor commands to generate saccadic eye movements toward targets. This study investigated the synaptic input patterns into vertical eye movement-related superior and inferior rectus motoneurons from the SC, using intracellular recording and SC stimulating techniques in anesthetized adult cats. I found that the responses obtained from these motoneurons consisted of complex components: a sequence of monosynaptic excitatory postsynaptic potentials (EPSPs), di- or trisynaptic EPSPs or inhibitory postsynaptic potentials (IPSPs) and polysynaptic EPSPs. The amplitudes of the latter two components nearly coincided with the motor map of the SC, which represented the correlation between the sites of SC stimulation and the directions and amplitudes of evoked saccades. I concluded that the SC elicits vertical eye movements through these di- or trisynaptic and polysynaptic pathways in the cat.

UI	MeSH Term	Description	Entries
D009046	Motor Neurons	Neurons which activate MUSCLE CELLS.	Neurons, Motor,Alpha Motorneurons,Motoneurons,Motor Neurons, Alpha,Neurons, Alpha Motor,Alpha Motor Neuron,Alpha Motor Neurons,Alpha Motorneuron,Motoneuron,Motor Neuron,Motor Neuron, Alpha,Motorneuron, Alpha,Motorneurons, Alpha,Neuron, Alpha Motor,Neuron, Motor
D001931	Brain Mapping	Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.	Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004525	Efferent Pathways	Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. Such impulses are conducted via efferent neurons (NEURONS, EFFERENT), such as MOTOR NEURONS, autonomic neurons, and hypophyseal neurons.	Motor Pathways,Efferent Pathway,Pathway, Efferent,Pathways, Efferent
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012438	Saccades	An abrupt voluntary shift in ocular fixation from one point to another, as occurs in reading.	Pursuit, Saccadic,Saccadic Eye Movements,Eye Movement, Saccadic,Eye Movements, Saccadic,Movement, Saccadic Eye,Movements, Saccadic Eye,Pursuits, Saccadic,Saccade,Saccadic Eye Movement,Saccadic Pursuit,Saccadic Pursuits
D013477	Superior Colliculi	The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching.	Colliculus, Superior,Optic Lobe, Human,Optic Lobe, Mammalian,Optic Tectum,Anterior Colliculus,Superior Colliculus,Tectum, Optic,Colliculi, Superior,Colliculus, Anterior,Human Optic Lobe,Human Optic Lobes,Mammalian Optic Lobe,Mammalian Optic Lobes,Optic Lobes, Human,Optic Lobes, Mammalian,Optic Tectums,Tectums, Optic