-transparent.png){kind=logo}
The metabolism of fluorene, a tricyclic aromatic hydrocarbon, by Cunninghamella elegans ATCC 36112 was investigated. Approximately 69% of the [9-14C]fluorene added to cultures was metabolized within 120 h. The major ethyl acetate-soluble metabolites were 9-fluorenone (62%), 9-fluorenol, and 2-hydroxy-9-fluorenone (together, 7.0%). Similarly to bacteria, C. elegans oxidized fluorene at the C-9 position of the five-member ring to form an alcohol and the corresponding ketone. In addition, C. elegans produced the novel metabolite 2-hydroxy-9-fluorenone.
Related Publications
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
February 2007,
Chemosphere,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
December 2007,
Steroids,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
September 2001,
Applied and environmental microbiology,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
September 2017,
Xenobiotica; the fate of foreign compounds in biological systems,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
January 2024,
Methods in enzymology,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
December 1995,
Drug metabolism and disposition: the biological fate of chemicals,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
November 2002,
Drug metabolism and disposition: the biological fate of chemicals,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
March 2010,
Applied microbiology and biotechnology,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
April 2007,
The Journal of antibiotics,
J V Pothuluri, and
J P Freeman, and
F E Evans, and
C E Cerniglia
October 1999,
Drug metabolism and disposition: the biological fate of chemicals,
