BIOMAT Database Logo BIOMAT Database Logo

Polychlorinated biphenyls (PCBs) and polychlorinated quaterphenyls (PCQs) concentrations in skin surface lipids and blood of patients with yusho. 1993

T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
Department of Dermatology, Nagasaki University School of Medicine.

The relationship between PCBs and PCQs concentrations in the skin surface lipids and blood was investigated in this study. PCBs and PCQs concentrations in thirty two patients with PCB poisoning (Yusho) and 20 normal controls were analyzed. The collection of skin surface lipids was performed by the method of cotton pad with 70% ethyl alcohol. The alkaline decomposition method described in the official standard analytical methods for the isolation of PCBs and PCQs fractions was used. In the blood of control group, mean value of PCBs concentration was 2.1 ng/g, and that of PCQs concentration was too low to be detected by our analytical method. On the other hand, the PCBs concentration in the Yusho group were two times higher than those in the control group. The mean value of PCQs concentration was 0.90 ng/g in Yusho group, while it was not detectable in the control group. In the skin surface lipids of patients with Yusho, the mean value of PCBs concentration was 580.0 ng/g, but was 324.4 ng/g in the control group. The mean value of PCQs concentration in the skin surface lipids of Yusho patients was 25.7 ng/g, although it was not detected in the control group. PCBs and PCQs levels in the skin surface lipids were higher than those in the blood. This means that cutaneous sebaceous system is one of the excreted systems of polyhalogenated chemicals, such as PCBs or PCQs, when these chemicals are precipitated in human or mammalians.

UI MeSH Term Description Entries
D008055 Lipids A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) Lipid
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011078 Polychlorinated Biphenyls Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants. PCBs,Polychlorinated Biphenyl,Polychlorobiphenyl Compounds,Biphenyl, Polychlorinated,Biphenyls, Polychlorinated,Compounds, Polychlorobiphenyl
D002722 Chlorobenzenes Aromatic organic compounds with the chemical formula C6H5Cln.
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

Related Publications

T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
[Polychlorinated biphenyls (PCBs) and polychlorinated quaterphenyls (PCQs) concentrations in skin surface lipids and blood of patients with Yusho].
May 1995, Fukuoka igaku zasshi = Hukuoka acta medica,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
PCBs, PCQs and PCDFs in blood of yusho and yu-cheng patients.
February 1985, Environmental health perspectives,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
[Polychlorinated biphenyls and polychlorinated quaterphenyls in human blood (author's transl)].
April 1981, Fukuoka igaku zasshi = Hukuoka acta medica,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
Concentration of hydroxylated polychlorinated biphenyls (OH-PCBs) in the blood of Yusho patients in 2010.
April 2013, Fukuoka igaku zasshi = Hukuoka acta medica,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
[Analysis of polychlorinated quaterphenyls in Yusho diagnosis].
May 2005, Fukuoka igaku zasshi = Hukuoka acta medica,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
PCBs, PCQs and PCDFs in tissues of yusho and yu-cheng patients.
February 1985, Environmental health perspectives,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
[A longitudinal analysis on the association of serum lipids and lipoproteins concentrations with blood polychlorinated biphenyls level in chronic "Yusho" patients].
May 2003, Fukuoka igaku zasshi = Hukuoka acta medica,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
[PCBs and PCQs in the blood of yusho patients and workers occupationally exposed to PCBs and their health status].
May 1983, Fukuoka igaku zasshi = Hukuoka acta medica,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
[Studies on the application of residual PCBs, PCQs and PCDFs concentrations to Yusho diagnosis].
May 1991, Fukuoka igaku zasshi = Hukuoka acta medica,
T Ohgami, and M Watanabe, and K Tanaka, and H Yoshida, and S Nonaka, and N Tsukazaki, and Y Rikioka
[Analysis of polychlorinated quaterphenyls in Yusho diagnosis in 2005].
May 2007, Fukuoka igaku zasshi = Hukuoka acta medica,
Copied contents to your clipboard!