Biomaterial Database

Effect of imidocarb dipropionate and hemicastration on spermatogenesis in pony stallions. 1977

W M Frerichs

The effect of imidocarb dipropionate [3, 3' bis-(2-imidazolin-2-yl) carbanilide dipropionate] on spermatogenesis in 3 pony stallions was studied. The drug alone had no deleterious effect on spermatogenesis when given intramuscularly 4 times at a dosage level of 4 mg/kg at 72-hour intervals. Hemicastration, with or without subsequent drug treatment, caused almost complete cessation of spermatogenesis 30 days after the operation.

UI	MeSH Term	Description	Entries
D007095	Imidocarb	One of ANTIPROTOZOAL AGENTS used especially against BABESIA in livestock. Toxicity has been reported.	Imidocarb Dihydrochloride,Imidocarb Hydrochloride,Dihydrochloride, Imidocarb,Hydrochloride, Imidocarb
D008297	Male		Males
D002224	Carbanilides	Compounds consisting of two phenyl groups joined by a urea. Derivatives may be used as ANTIPARASITIC AGENTS.	Diphenylurea Compounds,Compounds, Diphenylurea
D002369	Castration	Surgical removal or artificial destruction of gonads.	Gonadectomy,Castrations,Gonadectomies
D006736	Horses	Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.	Equus caballus,Equus przewalskii,Horse, Domestic,Domestic Horse,Domestic Horses,Horse,Horses, Domestic
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013091	Spermatogenesis	The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.	Spermatocytogenesis,Spermiogenesis