-transparent.png){kind=logo}
We measured serum, blood, or red cell concentrations of various vitamins in 24 patients with Crohn's disease who had been free from any nutritional treatment, and compared them with those in 24 healthy controls. Twelve of the patients were affected in the small bowel only, two in the large bowel only, and the remaining 10 in both the small and large bowel. The fat-soluble vitamins A and E were significantly decreased in patients with Crohn's disease compared to controls. Among the water-soluble vitamins, vitamins B1, B2 and B6 and folic acid were more depleted in patients with Crohn's disease than in the controls, whereas vitamins B12 and C, nicotinic acid, and biotin were not different between the two groups, and pantothenic acid was increased in patients with Crohn's disease. In addition, vitamin B2 and nicotinic acid showed a negative correlation with the Crohn's disease activity index. These findings suggest that there is a variety of vitamin deficiencies in Crohn's disease prior to treatment and also that concentrations of some vitamins, such as vitamin B2 and nicotinic acid, may reflect the severity of the disease.
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
November 1985,
Gut,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
January 1987,
Digestion,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
March 2020,
Zhonghua yi xue za zhi,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
October 2017,
Nutrients,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
July 2011,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
January 2019,
Intestinal research,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
January 2008,
Inflammatory bowel diseases,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
May 2006,
Zhonghua yi xue za zhi,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
August 2003,
Alimentary pharmacology & therapeutics,
F Kuroki, and
M Iida, and
M Tominaga, and
T Matsumoto, and
K Hirakawa, and
S Sugiyama, and
M Fujishima
October 2016,
Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society,
