-transparent.png){kind=logo}
The effects of gonadectomy and testosterone treatment on the fine structure of the Harderian gland in male and female green frogs were investigated in different periods of the year. Gonadectomy, carried out when the glands are in the lowest secretory phase (September), causes degenerative changes consisting of a reduction of the rough endoplasmic reticulum, the appearance of autolysosomes, and an increase of nuclear heterochromatin. These effects can be prevented by testosterone treatment. No castration effects are found during the recovery (November) and enhancement (April-May) phases of secretory activity. The results suggest that the frog Harderian gland's sensitivity to testosterone changes during the annual cycle. The androgen dependence of the Harderian gland is correlated with the presence of androgen receptors in both male and female frogs.
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
January 1995,
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
August 1995,
Zoological science,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
January 1990,
Comparative biochemistry and physiology. A, Comparative physiology,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
May 1991,
The Journal of endocrinology,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
September 1995,
Comparative biochemistry and physiology. Part A, Physiology,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
January 1989,
Basic and applied histochemistry,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
December 1994,
The Journal of steroid biochemistry and molecular biology,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
January 1998,
Life sciences,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
June 2002,
The Journal of experimental zoology,
G Chieffi-Baccari, and
L D'Matteo, and
M d'Istria, and
S Minucci, and
I Serino, and
B Varriale
August 2005,
Journal of cellular physiology,
