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The effect of a single injection of pentagastrin on diamine oxidase (DAO) activity in the rat intestinal mucosa was examined. The animals of subsequent groups were sacrificed by decapitation at 6, 12 and 24 h after the administration of pentagastrin or 0.9% NaCl (controls). Diamine oxidase activity was also tested in entire animals. The intestinal fragments were rinsed with 0.9% NaCl. The mucosal scrapings were frozen in liquid nitrogen. Diamine oxidase activity increased in the 24 h after the administration of pentagastrin, when compared with respective controls. No significant differences at other times were evident. The present data are in agreement with the hypothesis that DAO is an enzyme involved in the negative feedback control mechanism of intestinal mucosa cell proliferation.
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
July 1988,
The American journal of gastroenterology,
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
April 1995,
Inflammation research : official journal of the European Histamine Research Society ... [et al.],
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
February 1981,
Gastroenterology,
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
April 1987,
Agents and actions,
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
October 1998,
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E Wajs, and
M Szkudliński, and
A Lewiński, and
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M Karbownik, and
I Rybicka
July 1981,
Gastroenterology,
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
April 1988,
Agents and actions,
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
April 1989,
Agents and actions,
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
March 1991,
The Journal of surgical research,
E Wajs, and
M Szkudliński, and
A Lewiński, and
W A Fogel, and
M Karbownik, and
I Rybicka
December 1977,
Biochemical pharmacology,
