Risk factors for persistent diarrhea among children under 2 years of age. Case control study. 1993

N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
Advance Center for Clinical, Epidemiological Research and Training (ACCERT), Madras Medical College, Institute of Child Health.

A case control study was done at the Institute of Child Health, Madras, among prospectively recruited children aged 1-23 months to identify the risk factors for persistent diarrhea. Cases were children with diarrhea persisting for > 14 days. Controls were children with acute diarrhea who had recovered within 7 days. Two controls for each case, matched for age were recruited. The total number of cases and controls recruited were 170 and 340. Fifteen risk factors for association with persistent diarrhea were studied. When the factors were adjusted for covariables by logistic regression, only 6 factors were found to be significant, namely, malnutrition (OR 2.9; 95% CI 1.9-4.5), dysenteric stools (OR 2.4; 95% CI 1.3-4.3), indiscriminate use of antimicrobials (OR 2.4; 95% CI 1.6-3.9), associated illnesses (OR 2.1; 95% CI 1.5-3.1), stools > 10/day (OR 1.8; 95% CI 1.2-2.8) and persistence of dehydration (OR 1.4; 95% CI 1.2-1.7). However, when invasive diarrhea was excluded, weight loss during study period became a significant factor. It is concluded that all children with acute diarrhea should be investigated for associated illnesses and treated adequately, indiscriminate use of antimicrobials should be avoided and nutritional support should be provided.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D002908 Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D003968 Diarrhea, Infantile DIARRHEA occurring in infants from newborn to 24-months old. Infantile Diarrhea,Diarrheas, Infantile,Infantile Diarrheas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D016022 Case-Control Studies Comparisons that start with the identification of persons with the disease or outcome of interest and a control (comparison, referent) group without the disease or outcome of interest. The relationship of an attribute is examined by comparing both groups with regard to the frequency or levels of outcome over time. Case-Base Studies,Case-Comparison Studies,Case-Referent Studies,Matched Case-Control Studies,Nested Case-Control Studies,Case Control Studies,Case-Compeer Studies,Case-Referrent Studies,Case Base Studies,Case Comparison Studies,Case Control Study,Case Referent Studies,Case Referrent Studies,Case-Comparison Study,Case-Control Studies, Matched,Case-Control Studies, Nested,Case-Control Study,Case-Control Study, Matched,Case-Control Study, Nested,Case-Referent Study,Case-Referrent Study,Matched Case Control Studies,Matched Case-Control Study,Nested Case Control Studies,Nested Case-Control Study,Studies, Case Control,Studies, Case-Base,Studies, Case-Comparison,Studies, Case-Compeer,Studies, Case-Control,Studies, Case-Referent,Studies, Case-Referrent,Studies, Matched Case-Control,Studies, Nested Case-Control,Study, Case Control,Study, Case-Comparison,Study, Case-Control,Study, Case-Referent,Study, Case-Referrent,Study, Matched Case-Control,Study, Nested Case-Control

Related Publications

N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
January 2001, Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
January 2003, Cadernos de saude publica,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
December 2023, Clinical and experimental pediatrics,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
March 2016, The American journal of tropical medicine and hygiene,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
December 2000, Journal of clinical microbiology,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
January 1985, Przeglad epidemiologiczny,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
December 2016, Burns : journal of the International Society for Burn Injuries,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
December 1988, American journal of epidemiology,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
January 1988, Przeglad epidemiologiczny,
N Deivanayagam, and N Mala, and T P Ashok, and S R Ratnam, and V S Sankaranarayanan
November 2013, Burns : journal of the International Society for Burn Injuries,
Copied contents to your clipboard!