Eight hundred forty consecutive male patients were examined for the presence of pearly penile papules. The age, race and presence or absence of circumcision were recorded. Two hundred fifty-three (30.1%) of patients had lesions, and there was a significantly increased incidence of pearly penile papules in Negroes and uncircumcised men. A significantly greater proportion of Negroes were uncircumcised, possibly explaining the racial difference. The incidence of papules was greatest in young adults and tended to decrease with increasing age. A higher percentage of men over 40 had pearly penile papules than previously reported.