-transparent.png){kind=logo}
A study of 140 patients with B-cell chronic lympoheucosis using flow cytometry of DNA of lymphocytes evidences an interrelation between the severity of the clinical course of the disease and state of lymphocyte DNA. The authors propose to distinguish 2 variants of chronic lympholeucosis: accumulative and proliferative. In the former DNA ploidy and kinetics of tumour lymphocytes did not differ from that in the healthy; in the latter--progression of the disease depended on S-phase lymphocyte contact. Progression of the severity of chronic lympholeucosis is accompanied by marked increase of polyploid cell in the S-phase that may be a criterion for early diagnosis of malignant transformation of chronic lympholeucosis.
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
July 1997,
The Journal of urology,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
September 1989,
The Journal of urology,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
August 1994,
The Journal of urology,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
September 1991,
The Journal of thoracic and cardiovascular surgery,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
December 1986,
Surgery,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
January 1990,
Eksperimental'naia onkologiia,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
January 1996,
The West Virginia medical journal,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
September 1978,
Problemy gematologii i perelivaniia krovi,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
February 1983,
Gematologiia i transfuziologiia,
E T Dudko, and
L M Tishchenko, and
A K Kalinovskiĭ, and
V B Krivozubov
December 1987,
Surgery,
