Biomaterial Database

Fumonisins and other inhibitors of de novo sphingolipid biosynthesis. 1993

A H Merrill, and E Wang, and D G Gilchrist, and R T Riley

Department of Biochemistry, Rollins Research Center, Emory University School of Medicine, Atlanta, Georgia 30322.

UI	MeSH Term	Description	Entries
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D009183	Mycotoxins	Toxic compounds produced by FUNGI.	Fungal Toxins,Mycotoxin,Toxins, Fungal
D000581	Amidohydrolases	Any member of the class of enzymes that catalyze the cleavage of amide bonds and result in the addition of water to the resulting molecules.	Amidases,Amidohydrolase
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013107	Sphingolipids	A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)	Lysosphingolipids,Sphingolipid
D055572	Ceramidases	Amidohydrolases that are specific for the cleavage of the N-acyl linkage of CERAMIDES. Ceramidases are classified as acidic, neutral or basic according to the optimal pH with which they function.	Acylsphingosine Deacylase,Ceramidase,N-Acylsphingosine Amidohydrolase,Amidohydrolase, N-Acylsphingosine,Deacylase, Acylsphingosine,N Acylsphingosine Amidohydrolase