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The relationship between n-hexane exposure and neurological symptoms and signs, and sensitivity to peripheral vibration, was investigated in 126 metal can manufacturing workers. Exposed workers were significantly more likely than unexposed workers to report at least one neurological symptom of the limbs. Highly exposed workers were able to detect tuning fork vibration for significantly shorter periods than unexposed workers, independent of the effects of age, height, sex, alcohol, and education. A tuning fork was more capable than the Vibratron of detecting neurotoxic effects of n-hexane.
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