Biomaterial Database

Mouthrinses in the prevention and treatment of periodontal disease. 1993

K Baker

University of Iowa, College of Dentistry, Iowa City.

Although the ideal topical antimicrobial does not exist, some marketed products possess many of the desirable characteristics of such an agent. Antimicrobial agents from a number of different chemical categories are being evaluated continuously. Recent clinical trials evaluating the effectiveness of chlorhexidine, stannous fluoride, prebrushing rinses, phenolic compounds, cetylpyridinium chloride, and new agents such as triclosan are described. Other trials involving special patient groups such as the elderly, mentally handicapped, and orthodontic patients, are discussed. Recent articles on alternative roles for topical antimicrobials are also identified.

UI	MeSH Term	Description	Entries
D007546	Isoquinolines	A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
D009025	Morpholines		Tetrahydro-1,4-Oxazines,Tetrahydro 1,4 Oxazines
D009067	Mouthwashes	Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)	Mouth Bath,Mouth Rinse,Mouth Wash,Bath, Mouth,Baths, Mouth,Mouth Baths,Mouth Rinses,Rinse, Mouth,Rinses, Mouth,Wash, Mouth
D009971	Orthodontics, Corrective	The phase of orthodontics concerned with the correction of malocclusion with proper appliances and prevention of its sequelae (Jablonski's Illus. Dictionary of Dentistry).	Corrective Orthodontics
D010510	Periodontal Diseases	Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.	Parodontosis,Pyorrhea Alveolaris,Disease, Periodontal,Diseases, Periodontal,Parodontoses,Periodontal Disease
D002594	Cetylpyridinium	Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.	Angifonil,Biosept,Catamium,Ceepryn Chloride,Cetamium,Cetylpyridinium Chloride,Cetylpyridinium Chloride Anhydrous,Cetylpyridium,Cetylyre,Dobendan,Hexadecylpyridinium,Merocets,Pristacin,Pyrisept,Sterogenol,Anhydrous, Cetylpyridinium Chloride,Chloride Anhydrous, Cetylpyridinium,Chloride, Ceepryn,Chloride, Cetylpyridinium
D002710	Chlorhexidine	A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.	Chlorhexidine Acetate,Chlorhexidine Hydrochloride,MK-412A,Novalsan,Sebidin A,Tubulicid,Acetate, Chlorhexidine,Hydrochloride, Chlorhexidine,MK 412A,MK412A
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults