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A case-control study on the association between genetic markers (ABO, Rh, MNSs and sex) and typhoid fever (TF) was performed. We found that (a) the B allele conferred protection to females for TF and a mild susceptibility to males; (b) the CDe haplotype (or the RH3 phenotype, mostly CDe/CDe) was associated with protection against Salmonella in both sexes, while cDE (or RH7, mostly cDE/cDE, and RH8, mostly cDE/cde) was associated with susceptibility to TF, and (c) heterozygotes Ss (MNSs system) had a high susceptibility, while SS and particularly ss homozygotes seemed to be protected for the disease. There were very significant interactions among the blood systems and sex.
C Y Valenzuela, and
P Herrera
November 1966,
American journal of human genetics,
C Y Valenzuela, and
P Herrera
November 1993,
Journal of forensic sciences,
C Y Valenzuela, and
P Herrera
November 1999,
American journal of human biology : the official journal of the Human Biology Council,
C Y Valenzuela, and
P Herrera
June 1979,
Nihon rinsho. Japanese journal of clinical medicine,
C Y Valenzuela, and
P Herrera
January 2003,
Medicinski pregled,
C Y Valenzuela, and
P Herrera
May 1985,
Revista medica de Chile,
C Y Valenzuela, and
P Herrera
January 1973,
Haematologia,
C Y Valenzuela, and
P Herrera
January 1985,
Human genetics,
C Y Valenzuela, and
P Herrera
August 1983,
British journal of urology,
C Y Valenzuela, and
P Herrera
October 1965,
Wiener klinische Wochenschrift,
