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Major risk factors for coronary heart disease include hypertension, high serum cholesterol and triglyceride levels, and cigarette smoking. Minor risk factors include glucose intolerance, electrocardiographic changes, and personality type. Often the initial manifestation is angina pectoris. To prevent coronary heart disease, physicians need to know the answers to the following questions: (1) In which person will coronary heart disease develop, and when? (2) What is the cause? (3) What major and minor causative factors can be modified? (4) How can these modifications be achieved in a free-living, working, well population? (5) What is the earliest manifestation of coronary atherosclerosis? (6) What special diagnostic procedures are useful in coronary heart disease? These subjects are examined briefly.
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M N Kotler, and
W Likoff
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B L Segal, and
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B L Segal, and
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