[Complex evaluation of risk factors in patients after myocardial infarction]]. 1993

E Simon, and G Domján
Allami Szanatórium, Sopron.

In this work the authors have constructed a clinical epidemiological score system for characterizing the severity of the diseased state of our 85 patients got over myocardial infarction. The important role is commonly known which is played by the free radical processes in the pathogenesis of the heart infarct. From these free radical reactions the authors have focused their attention to studying the lipid peroxides. Beside the determinations of the malondialdehyde content of native serums they have measured the intensity of the malondialdehyde development in the free radical system generated by hydrogen-peroxide in vitro treatment of serums. With the help of the newly elaborated and applied method they have obtained a 67.11% average increase of the amount of malondialdehyde developed in vitro in comparison with the mean malondialdehyde value measured in the same analytical conditions with 154 healthy controls. They have made a statistical calculation for studying the question if there is any relationship between the scores of the age of patients and the malondialdehyde values of hydrogen-peroxide treated serums. On the basis of results of biochemical measurements and statistical analyses it seems very important to pay more attention both to the intensity of free radical reactions and the patients age in the severity's relations of the diseased state at heart infarct patients.

UI MeSH Term Description Entries
D008297 Male Males
D008315 Malondialdehyde The dialdehyde of malonic acid. Malonaldehyde,Propanedial,Malonylaldehyde,Malonyldialdehyde,Sodium Malondialdehyde,Malondialdehyde, Sodium
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D005260 Female Females
D005609 Free Radicals Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated. Free Radical
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D015227 Lipid Peroxidation Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor. Lipid Peroxidations,Peroxidation, Lipid,Peroxidations, Lipid

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