Currently the treatment of choice for OM is an oral antimicrobial agent, but selecting a specific agent should include consideration of efficacy, adverse effect profile, compliance, and cost. The use of adjunctive medications like decongestants for specific subtypes of OM has been debated in the literature, but efficacy has not been proven. As knowledge about the pathogenesis of OM is further refined, new treatment modalities for OM will be introduced. Because pharmacists are involved daily with pediatric patients who experience OM, they have an important role in making sure that patients receive appropriate therapy. A patient's profile should be checked for allergies and concurrent medications when a prescription for an antimicrobial agent is presented for a child with OM. The parents should be counseled about the administration, storage, and general product use as well as potential adverse effects, duration of use, and the need for compliance. An administration device for drug delivery like an oral syringe should be provided. Parents need advice from the pharmacist in making sure their children receive the best possible pharmaceutical care.