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Lincomycin levels in the blood serum and lung tissue were determined in 17 patients after surgical operations because of the lung diseases, the drug being administered in a dose of 500 mg. In 45 to 330 minutes after administration of the antibiotic its concentration in the blood serum and lung tissue was 4.6 +/- 10 lambda/ml(average 7.7 lambda/ml) and 1.4-8 lambda/gm (average 4.4 lambda/gm) respectively. The lincomycin level in the lung tissue amounted to 61 per cent of that in the blood setum. The concentration of lincomycin the lung tissue was several times higher than the minimum level necessary for inhibition of the strains included in the antibiotic antibacterial spectrum. Therefore, lincomycin is an important drug in the treatment of infections of the respiratory tract.
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
January 1983,
Medicina,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
October 1969,
Arzneimittel-Forschung,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
July 1982,
The Japanese journal of antibiotics,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
June 1991,
Hinyokika kiyo. Acta urologica Japonica,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
January 1979,
Arzneimittel-Forschung,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
June 1971,
American journal of ophthalmology,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
February 1968,
Arzneimittel-Forschung,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
June 1987,
The Journal of the Association of Physicians of India,
E Faragó, and
J Kiss, and
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Z Nabrady
July 1973,
Die Medizinische Welt,
E Faragó, and
J Kiss, and
S Kollár, and
Z Nabrady
March 2004,
The Journal of clinical endocrinology and metabolism,
