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In a study of two groups of healthy males matched for age, smoking habits, and duration of follow-up, but differing in the rapidity of decline of FEV1 and/or vital capacity (VC), we measured lung volumes before and after bronchodilator inhalation, forced expiratory flows, diffusion capacity for CO (DLCO), and total respiratory impedance. A discriminant analysis showed that the separation between the two groups was achieved best by DLCO, weight, and FEV1/VC among the smokers and by body height and DLCO among the nonsmokers. The fact that DLCO turns out to discriminate between people with a rapid and a normal spirographic decline in the present group points to the possibility of using this measurement, in combination with FEV1/VC and weight, as a predictor of rapid decline of lung function in middle-aged healthy male smokers.
M Cauberghs, and
J Clement, and
K P Van de Woestijne
April 1991,
Hospital practice (Office ed.),
M Cauberghs, and
J Clement, and
K P Van de Woestijne
January 1981,
The Journal of asthma : official journal of the Association for the Care of Asthma,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
June 1974,
International journal of epidemiology,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
October 1985,
Thorax,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
April 1987,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
January 1974,
Annals of surgery,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
July 1998,
Applied human science : journal of physiological anthropology,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
June 2021,
Clinical journal of the American Society of Nephrology : CJASN,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
April 2021,
Kidney international,
M Cauberghs, and
J Clement, and
K P Van de Woestijne
January 2023,
Frontiers in immunology,
