BIOMAT Database Logo BIOMAT Database Logo

RS-61443/cyclosporine combination therapy prolongs canine liver allograft survival. 1993

W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
Department of Surgery, University of Wisconsin Medical School, Madison.

UI MeSH Term Description Entries
D007166 Immunosuppressive Agents Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. Immunosuppressant,Immunosuppressive Agent,Immunosuppressants,Agent, Immunosuppressive,Agents, Immunosuppressive
D009173 Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION. Cellcept,Mycophenolate Mofetil,Mycophenolate Mofetil Hydrochloride,Mycophenolate Sodium,Mycophenolic Acid Morpholinoethyl Ester,Myfortic,RS 61443,RS-61443,Sodium Mycophenolate,Mofetil Hydrochloride, Mycophenolate,Mofetil, Mycophenolate,Mycophenolate, Sodium,RS61443
D011239 Prednisolone A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states. Di-Adreson-F,Predate,Predonine,Di Adreson F,DiAdresonF
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004359 Drug Therapy, Combination Therapy with two or more separate preparations given for a combined effect. Combination Chemotherapy,Polychemotherapy,Chemotherapy, Combination,Combination Drug Therapy,Drug Polytherapy,Therapy, Combination Drug,Chemotherapies, Combination,Combination Chemotherapies,Combination Drug Therapies,Drug Polytherapies,Drug Therapies, Combination,Polychemotherapies,Polytherapies, Drug,Polytherapy, Drug,Therapies, Combination Drug
D005260 Female Females
D006085 Graft Survival The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. Graft Survivals,Survival, Graft,Survivals, Graft
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014184 Transplantation, Homologous Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals. Transplantation, Allogeneic,Allogeneic Grafting,Allogeneic Transplantation,Allografting,Homografting,Homologous Transplantation,Grafting, Allogeneic

Related Publications

W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
Prolongation of canine intestinal allograft survival with RS-61443, cyclosporine, and prednisone.
February 1993, Transplantation proceedings,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
Prolongation of canine intestinal allograft survival with RS-61443, cyclosporine, and prednisone.
April 1993, Transplantation,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
Low-dose combination therapy of DUP-785 and RS-61443 prolongs cardiac allograft survival in rats.
January 1992, Transplant international : official journal of the European Society for Organ Transplantation,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
Enhancement of allograft survival by combination RS-61443 and DUP-785 therapy.
April 1993, Transplantation,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
DAB486-IL-2 (IL-2-toxin) in combination with low-dose RS-61443 (mycophenolate mofetil) prolongs murine thyroid allograft survival.
February 1993, Transplantation proceedings,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
The effect of a nonsteroid immunosuppressive regimen with RS-61443 and cyclosporine on kidney allograft survival in dogs.
April 1996, Transplantation proceedings,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
Immunosuppressive effect of RS-61443 on rat cardiac allograft survival in combination with leflunomide or FK 506.
April 1996, Transplantation proceedings,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
RS-61443 reverses acute allograft rejection in dogs.
October 1991, Surgery,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
Transdermal application of cyclosporine prolongs skin allograft survival.
April 1988, Transplantation proceedings,
W O Bechstein, and M Schilling, and D M Steele, and D A Hullett, and H W Sollinger
RS-61443 reverses acute renal allograft rejection in dogs.
January 1992, Transplant international : official journal of the European Society for Organ Transplantation,
Copied contents to your clipboard!