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POU domain genes encode a family of highly conserved transacting factors that influence the transcriptional activity of several cell type-specific and ubiquitous genes. We have cloned and sequenced cDNAs encoding a novel mouse POU domain protein, Oct-11, that is closely related within the POU domain to the POU class II proteins, Oct-1 and Oct-2. Recombinant Oct-11 protein binds specifically to an octamer sequence in vitro. The Oct-11 gene is expressed during mouse embryogenesis and in the adult thymus and testis. In addition, it is abundant in the myeloma cell line P3/NS-1/1-Ag4.1. We describe the structure of Oct-11 and its chromosomal localization, and discuss the evidence that the POU class II gene family has evolved by duplication and divergence of a common ancestral gene.
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
July 2013,
Archives of dermatological research,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
February 2002,
Brain research,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
February 1992,
Molecular and cellular biology,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
August 2010,
Animal science journal = Nihon chikusan Gakkaiho,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
March 2007,
The Journal of biological chemistry,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
November 1997,
Genomics,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
February 1997,
Human molecular genetics,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
May 1994,
Human genetics,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
November 1993,
Journal of animal science,
A S Goldsborough, and
L E Healy, and
N G Copeland, and
D J Gilbert, and
N A Jenkins, and
K R Willison, and
A Ashworth
January 1996,
World journal of urology,
