[Reticulocytes--new possibilities with automated counting]. 1993

L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
Sentrallaboratoriet, Det Norske Radiumhospital, Oslo.

A fully automated reticulocyte counter, Sysmex R-1000 has been evaluated at three Norwegian hospitals. The instrument measures fluorescence-labelled RNA in the reticulocytes by flow cytometry. It also generates information on reticulocyte maturity. Instrument precision was superior to that achieved with the routine visual counting method. Samples preserved at room temperature remain stable for one day, whereas samples preserved at 5 degrees C remain stable for four days. An increasing number of reticulocytes is often the first sign of marrow regeneration after bone marrow transplantation or treatment of leukaemia with cytostatica. In patients with chronic renal failure who are receiving erythropoietin, the increase in reticulocytes is seen within days, and precedes the increase in haemoglobin by 2-3 weeks.

UI MeSH Term Description Entries
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D012156 Reticulocytes Immature ERYTHROCYTES. In humans, these are ERYTHROID CELLS that have just undergone extrusion of their CELL NUCLEUS. They still contain some organelles that gradually decrease in number as the cells mature. RIBOSOMES are last to disappear. Certain staining techniques cause components of the ribosomes to precipitate into characteristic "reticulum" (not the same as the ENDOPLASMIC RETICULUM), hence the name reticulocytes. Reticulocyte
D001800 Blood Specimen Collection The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc. Blood Specimen Collections,Collection, Blood Specimen,Collections, Blood Specimen,Specimen Collection, Blood,Specimen Collections, Blood
D004906 Erythrocyte Count The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD. Blood Cell Count, Red,Erythrocyte Number,Red Blood Cell Count,Count, Erythrocyte,Counts, Erythrocyte,Erythrocyte Counts,Erythrocyte Numbers
D005434 Flow Cytometry Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake. Cytofluorometry, Flow,Cytometry, Flow,Flow Microfluorimetry,Fluorescence-Activated Cell Sorting,Microfluorometry, Flow,Cell Sorting, Fluorescence-Activated,Cell Sortings, Fluorescence-Activated,Cytofluorometries, Flow,Cytometries, Flow,Flow Cytofluorometries,Flow Cytofluorometry,Flow Cytometries,Flow Microfluorometries,Flow Microfluorometry,Fluorescence Activated Cell Sorting,Fluorescence-Activated Cell Sortings,Microfluorimetry, Flow,Microfluorometries, Flow,Sorting, Fluorescence-Activated Cell,Sortings, Fluorescence-Activated Cell
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
January 1976, IEEE transactions on bio-medical engineering,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
August 2010, Medizinische Klinik (Munich, Germany : 1983),
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
September 1948, Nature,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
August 1946, La Presse medicale,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
January 2000, Postepy higieny i medycyny doswiadczalnej,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
January 1966, Laboratornoe delo,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
March 1965, Journal of clinical pathology,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
May 2018, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
March 2003, Klinicheskaia laboratornaia diagnostika,
L G Dalbak, and L Theodorsen, and M W Aune, and S Sandberg
June 2001, Seminars in thrombosis and hemostasis,
Copied contents to your clipboard!