Biomaterial Database

Immobilization and anesthesia of two hand-reared zebras. 1993

H C Lin, and J C Thurmon, and G J Benson, and W J Tranquilli

Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana 61801.

This report describes our experiences with 2 drug combinations that were used safely and effectively to immobilize and anesthetize 2 hand-reared zebras. Zebras were sedated with xylazine hydrochloride or detomidine. The latter is more potent and of more use in healthy, vigorous animals. Anesthesia was induced with thiamylal/guaifenesin or tiletamine/zolazepam. The latter is more convenient because a quick, simple IV injection will preclude the necessity for physical restraint required to administer a large volume of guaifenesin/thiobarbiturate combination. Tracheal intubation was easily accomplished with either induction regimen, and inhalation anesthetic was used for longer periods of anesthesia.

UI	MeSH Term	Description	Entries
D006993	Hypnotics and Sedatives	Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.	Hypnotic,Sedative,Sedative and Hypnotic,Sedatives,Hypnotic Effect,Hypnotic Effects,Hypnotics,Sedative Effect,Sedative Effects,Sedatives and Hypnotics,Effect, Hypnotic,Effect, Sedative,Effects, Hypnotic,Effects, Sedative,Hypnotic and Sedative
D007093	Imidazoles	Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
D007103	Immobilization	The restriction of the MOVEMENT of whole or part of the body by physical means (RESTRAINT, PHYSICAL) or chemically by ANALGESIA, or the use of TRANQUILIZING AGENTS or NEUROMUSCULAR NONDEPOLARIZING AGENTS. It includes experimental protocols used to evaluate the physiologic effects of immobility.	Hypokinesia, Experimental,Experimental Hypokinesia,Experimental Hypokinesias,Hypokinesias, Experimental
D008297	Male		Males
D010527	Perissodactyla	An order of ungulates having an odd number of toes, including the horse, tapir, and rhinoceros. (Dorland, 27th ed)	Perissodactylas
D011859	Radiography	Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film).	Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D006140	Guaifenesin	An expectorant that also has some muscle relaxing action. It is used in many cough preparations.	Guaiacol Glyceryl Ether,Guaiphenesin,Breonesin,Glycerol Guaiacolate,Guaiphenezine,Guiatuss,Humibid,Hytuss,My-301,Scott-Tussin,Ether, Guaiacol Glyceryl,Glyceryl Ether, Guaiacol,Guaiacolate, Glycerol,My 301,My301,Scott Tussin,ScottTussin
D006221	Halothane	A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)	1,1,1-Trifluoro-2-Chloro-2-Bromoethane,Fluothane,Ftorotan,Narcotan
D006724	Hoof and Claw	Highly keratinized processes that are sharp and curved, or flat with pointed margins. They are found especially at the end of the limbs in certain animals.	Claw,Claw and Hoof,Claws and Hooves,Hoof,Hooves,Hooves and Claws,Claws,Hoofs
D000758	Anesthesia	A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.