Biomaterial Database

[The effect of Partusisten on the maternal and fetal metabolism, acid-base balance and blood gases intrapartum (author's transl)]. 1977

V Lehmann

Following i.v. injection of 50 g of Partusisten into the mother there occurs, already within 5 min., a rise in the lactate concentration which reaches its peak after 25--30 min. After 25 min, a similar can be shown in the fetus. The fetal pO2 at this time has risen significantly to 2.1 mmHg, while the pCO2 has fallen by 3 mmHg. The increase in lactate concentration both in mother and fetus alters the acid base balance in both. pH is reduced and base deficit is raised, parallel in mother and fetus. The fetal acidosis is probably due to a lactate infusion from the mother.

UI	MeSH Term	Description	Entries
D007743	Labor, Obstetric	The repetitive uterine contraction during childbirth which is associated with the progressive dilation of the uterine cervix (CERVIX UTERI). Successful labor results in the expulsion of the FETUS and PLACENTA. Obstetric labor can be spontaneous or induced (LABOR, INDUCED).	Obstetric Labor
D007773	Lactates	Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.
D008431	Maternal-Fetal Exchange	Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission.	Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D010313	Partial Pressure	The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Partial Pressures,Pressure, Partial,Pressures, Partial
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011773	Pyruvates	Derivatives of PYRUVIC ACID, including its salts and esters.
D002245	Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.	Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D004983	Ethanolamines	AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.	Aminoethanols
D005260	Female		Females