An instrument for quantifying meibomian lipid on the lid margin: the Meibometer. 1993

C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
Nuffield Laboratory of Ophthalmology, University of Oxford, UK.

An instrument, the Meibometer, is described for estimating the casual level of meibomian lipid on the human eyelid margins, adapted from a commercially-available instrument used for measurement of skin surface lipid. A loop of plastic tape is pressed onto the everted lower lid margin to lift off a blot of lipid. The resultant change in light transmission of the tape is read by a photometer. Readings are not affected by side (R or L), time of day or lid surface temperature. After cleaning lipid from the lid margins with hexane, the rate of recovery per 10 blinks, as a percentage of the pre-cleaned level, was measured as 33.7 +/- 5.8 (mean +/- SE). This rate of delivery appears to provide enough lipid for complete resurfacing of the preocular tear film with every blink. Over short periods no detectable lipid was delivered in the absence of blinking.

UI MeSH Term Description Entries
D008055 Lipids A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) Lipid
D008297 Male Males
D008537 Meibomian Glands The sebaceous glands situated on the inner surface of the eyelids between the tarsal plates and CONJUNCTIVA. Glandulae Tarsales,Tarsal Glands,Gland, Meibomian,Gland, Tarsal,Meibomian Gland,Tarsal Gland
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009885 Ophthalmology A surgical specialty concerned with the structure and function of the eye and the medical and surgical treatment of its defects and diseases. Ocular Surgery,Ocular Surgeries,Surgery, Ocular
D001767 Blinking Brief closing of the eyelids by involuntary normal periodic closing, as a protective measure, or by voluntary action. Orbicularis Oculi Reflex,Reflex, Blink,Reflex, Corneal,Reflex, Orbicularis Oculi,Winking,Blink Reflexes,Corneal Reflexes,Orbicularis Oculi Reflexes,Blink Reflex,Reflexes, Blink,Reflexes, Orbicularis Oculi
D005143 Eyelids Each of the upper and lower folds of SKIN which cover the EYE when closed. Eyelid
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
June 2022, Cornea,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
February 1952, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
July 1992, Cornea,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
February 2022, Ophthalmology and therapy,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
September 2023, International ophthalmology,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
April 1977, Indian journal of ophthalmology,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
January 2018, Drug design, development and therapy,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
April 2011, The ocular surface,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
April 1999, The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc,
C K Chew, and C Jansweijer, and J M Tiffany, and S Dikstein, and A J Bron
April 1948, Archives of ophthalmology (Chicago, Ill. : 1929),
Copied contents to your clipboard!