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A 43-year-old female was admitted to our hospital for high blood pressure control. She showed hypokalemia with increased urinary potassium excretion, high plasma aldosterone concentration (33.9ng/dl, normal range; 2-12ng/dl) and reduced plasma renin activity (trace, normal range; 0.83-5ng/ml/hr). Bilateral adrenal tumors were revealed by abdominal computed tomography, and left adrenalectomy and right partial adrenalectomy were performed. Cytochromes p-450 and other enzymes involved in aldosterone synthesis were found predominantly in the tumor portions but not in the zona glomerulosa of the attached adrenals, which histopathologically showed paradoxical hyperplasia. This was a rare case of bilateral aldosterone-producing adrenal adenomas, which we could differentiate from idiopathic hyperaldosteronism by employing immunohistochemical analysis of steroidogenic enzymes.
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
January 2008,
QJM : monthly journal of the Association of Physicians,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
December 1996,
Internal medicine (Tokyo, Japan),
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
June 2016,
Journal of human hypertension,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
July 2007,
Kidney international,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
January 2016,
Endocrine journal,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
January 1970,
Progress in clinical cancer,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
April 2020,
Clinical nuclear medicine,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
January 2019,
Vitamins and hormones,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
November 2023,
JCEM case reports,
N Watanabe, and
K Abe, and
K Tsunoda, and
Y Imai, and
S Hsu-Lang, and
O Murakami, and
T Suzuki, and
K Sasano, and
K Yoshinaga
July 1981,
American journal of surgery,
